Annonce
relative à: egfr antibodies ihcEGFR Antibody LS-C213690 Rabbit Polyclonal Human EGFR with APC conjugate. IHC WB Flo ELISA IHC.
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30 janv. 2015 · Yu et al. developed a set of EGFR mutation–specific antibodies against EGFR with E746-A750 deletion and L858R for identification of mutant EGFR proteins by IHC, and reported a sensitivity of 92% and specificity of 99% as compared with direct DNA sequencing.
Find the EGFR antibody that fits your needs. Choose from 1 of 273 EGFR antibodies, which have been validated in experiments with 730 publications and 931 images featured in our data gallery. Browse primary antibodies for WB, Flow, IHC, ICC/IF, ELISA, IP, and other applications.
We previously demonstrated a high specificity of immunohistochemistry using epidermal growth factor receptor (EGFR) mutation-specific antibodies in lung adenocarcinoma and correlation with EGFR mutation analysis.
19 avr. 2013 · Our results show that EGFR mutation-specific antibodies could be an additional tool distinguishing primary versus metastatic carcinomas in the lung.
1 mai 2017 · The trial confirmed an excellent specificity with fairly good sensitivity of IHC with mutation-specific antibodies for common EGFR mutations and the accuracy of IHC testing for predicting response to EGFR TKIs.
EGFR expression is common in breast cancer, especially in triple-negative and basal-like breast carcinomas, and recent research has also found EGFR expressed in malignant bone and soft tissue cancers. Anti-EGFR is useful for detecting epithelioid and synovial sarcoma.
Recently, the monoclonal anti-EGFR antibody Necitumumab in combination with gemcitabine and cisplatin was approved (EMA/14106/2016) for first-line treatment of squamous non-small cell carcinoma (SqNSCLC). Eligibility was restricted to cases with positive EGFR expression.
