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1. pubmed.ncbi.nlm.nih.gov › 20935501APC/C-Cdh1: from cell cycle to cellular differentiation and ...

   pubmed.ncbi.nlm.nih.gov › 20935501

   1 oct. 2010 · Anaphase-promoting complex/cyclosome (APC/C) is a multifunctional ubiquitin-protein ligase that targets various substrates for proteolysis inside and outside of the cell cycle. The activation of APC/C is dependent on two WD-40 domain proteins, Cdc20 and Cdh1.

2. en.wikipedia.org › wiki › APCAPC/C activator protein CDH1 - Wikipedia

   en.wikipedia.org › wiki › APC

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   Cdh1 (cdc20 homolog 1) is one of the substrate adaptor proteins of the anaphase-promoting complex (APC) in the budding yeast Saccharomyces cerevisiae. Functioning as an activator of the APC/C, Cdh1 regulates the activity and substrate specificity of this ubiquitin E3-ligase.

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4. celldiv.biomedcentral.com › articles › 10The function of APC/C Cdh1 in cell cycle and beyond

   celldiv.biomedcentral.com › articles › 10

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   19 janv. 2009 · The anaphase promoting complex/cyclosome (APC/C) is a multi-subunit E3 ubiquitin ligase playing essential functions in mitosis. It is conserved from yeast to human and relies on two adaptor proteins, Cdc20 and Cdh1, to bring in substrates.

5. www.nature.com › articles › s41467/019/10375-xAPC/C CDH1 synchronizes ribose-5-phosphate levels and DNA ...

   www.nature.com › articles › s41467/019/10375-x

   7 juin 2019 · The low CDH1 or high TKTL1-induced accumulation of ribose-5-phosphate facilitates nucleotide and DNA synthesis as well as cell cycle progression in a ribose-5-phosphate-saturable manner.

6. www.nature.com › articles › s41467/024/47427-wReciprocal antagonism of PIN1-APC/C CDH1 governs mitotic ...

   www.nature.com › articles › s41467/024/47427-w

   15 avr. 2024 · Here, the authors reveal that a reciprocal inhibition of PIN1-APC/CCDH1 controls the cell cycle and mitotic protein degradation, offering a synergistic anti-tumor strategy.

7. www.nature.com › articles › s41598/022/14331-6Efficient terminal erythroid differentiation requires the APC ...

   www.nature.com › articles › s41598/022/14331-6

   21 juin 2022 · The APC/C-Cdh1 ubiquitin ligase complex drives proteosomal degradation of cell cycle regulators and other cellular proteins during the G1 phase of the cycle. The complex serves as an...

8. pubmed.ncbi.nlm.nih.gov › 19152694The function of APC/CCdh1 in cell cycle and beyond - PubMed

   pubmed.ncbi.nlm.nih.gov › 19152694

   19 janv. 2009 · The anaphase promoting complex/cyclosome (APC/C) is a multi-subunit E3 ubiquitin ligase playing essential functions in mitosis. It is conserved from yeast to human and relies on two adaptor proteins, Cdc20 and Cdh1, to bring in substrates.